Article
Autophagy genes are required for normal lipid levels in C. elegans.
Autophagy - 1 Mar 2013
Lapierre Louis R, Silvestrini Melissa J, Nuñez Lizbeth, Ames Kristina, Wong Sara, Le Thuc T, Hansen Malene, Meléndez Alicia
Abstract excerpt
Autophagy is a cellular catabolic process in which various cytosolic components are degraded. For example, autophagy can mediate lipolysis of neutral lipid droplets. In contrast, we here report that autophagy is required to facilitate normal levels of neutral lipids in C. elegans. Specifically, by using multiple methods to detect lipid droplets including CARS microscopy, we observed that mutants in the gene bec-...
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