Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IL28B genomic-based treatment paradigms for patients with chronic hepatitis C infection: the future of personalized HCV therapies.

The American journal of gastroenterology - 1 Jan 2011

Clark Paul J, Thompson Alex J, McHutchison John G

Abstract excerpt

Genome-wide association studies (GWAS) have recently identified host genetic variation to be critical for predicting treatment response and spontaneous clearance in patients infected with hepatitis C virus (HCV). These important new studies are reviewed and their future clinical implications discussed. Single-nucleotide polymorphisms in the region of the IL28B gene on chromosome 19, coding for the interferon...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Forecasting
Share to Gene Expression Regulation, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis C, Chronic

Share to Interferons

Share to Interleukins

Share to Precision Medicine

Share to Randomized Controlled Trials as Topic

Share to Ribavirin

Source

Identifiers

PMID: 20924369
DOI: 10.1038/ajg.2010.370

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IL28B genomic-based treatment paradigms for patients with chronic hepatitis C infection: the future of personalized HCV therapies.PMID 20924369Read ↗

IL28B polymorphism and genetic biomarkers of viral clearance in hepatitis C virus infection.Semantic proximity Read ↗

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance.Semantic proximity Read ↗

The recent breakthroughs in the understanding of host genomics in hepatitis C.Semantic proximity Read ↗

Role of IL28B for chronic hepatitis C treatment toward personalized medicine.Semantic proximity Read ↗

Association of Interleukin 28B Polymorphism with Clearance of Hepatitis C Virus: A Mini Review.Semantic proximity Read ↗

Novel findings for the development of drug therapy for various liver diseases: Genetic variation in IL-28B is associated with response to the therapy for chronic hepatitis C.Semantic proximity Read ↗

IL28B single nucleotide polymorphisms in the treatment of hepatitis C.Semantic proximity Read ↗

Genetic variation in IL28B and spontaneous clearance of hepatitis C virus.Semantic proximity Read ↗

Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study.Semantic proximity Read ↗

Host genomics and HCV treatment response.Semantic proximity Read ↗

Replicated association between an IL28B gene variant and a sustained response to pegylated interferon and ribavirin.Semantic proximity Read ↗

Natural history and clinical response: "it's the virus, stupid, or is it the host?".Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.