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Article

The structure of the 5'-untranslated region of mammalian poly(A) polymerase-alpha mRNA suggests a mechanism of translational regulation.

Molecular and cellular biochemistry - 1 Jul 2010

Rapti Aikaterini, Trangas Theoni, Samiotaki Martina, Ioannidis Panayotis, Dimitriadis Euthymios, Meristoudis Christos, Veletza Stavroula, Courtis Nelly

Abstract excerpt

Poly(A)polymerase-alpha (PAPOLA) has been the most extensively investigated mammalian polyadenylating enzyme, mainly in regard to its multifaceted post-translational regulation. The possibility of translational regulation of this enzyme was addressed. The transcription start site was mapped and two uORFs, highly conserved among several species, were identified in the 211-bp long, GC-rich, 5' UTR of the PAPOLA...

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PMID: 20174964
DOI: 10.1007/s11010-010-0405-x

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PAPOLA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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