Article
Transdominant human T-cell lymphotropic virus type I TAX1 mutant that fails to localize to the nucleus.
Journal of virology - 1 May 1991
Gitlin S D, Lindholm P F, Marriott S J, Brady J N
Abstract excerpt
Human T-cell lymphotropic virus type I (HTLV-I) encodes a 40-kDa nuclear transactivating phosphoprotein, TAX1. The results presented in this study demonstrate that deletion of amino acids 2 through 59 of TAX1 (delta 58 TAX1) decreased transactivation of the HTLV-I long terminal repeat 10- to 20-f...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Line
- Cell Nucleus
- Chlorocebus aethiops
- DNA, Viral
- Fluorescent Antibody Technique
- Gene Products, tax
- Genes, pX
- Human T-lymphotropic virus 1
- Molecular Sequence Data
