Article
TRAF5 is a downstream target of MAVS in antiviral innate immune signaling.
PloS one - 11 Feb 2010
Tang Eric D, Wang Cun-Yu
Abstract excerpt
The recognition of nucleic acids by the innate immune system during viral infection results in the production of type I interferons and the activation of antiviral immune responses. The RNA helicases RIG-I and MDA-5 recognize distinct types of cytosolic RNA species and signal through the mitochon...
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