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Article

TRAF3: A New Regulator of Type I Interferons

24 Mar 2006

Abstract excerpt

Type I interferons are a major and essential component of the mammalian antiviral response. While many cell types produce type I interferons following viral infection, how cells detect the virus has remained a mystery for many years. Recently, multiple genome-encoded viral recognition receptors have been identified. Interestingly, all of the major viral recognition pathways characterized thus far require TRAF3 to...

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PMID: 16582590
DOI: 10.4161/cc.5.8.2637

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