Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic and genetic alterations in duodenal carcinomas are distinct from biliary and ampullary carcinomas.

Gastroenterology - 1 May 2003

Kim Sang Geol, Chan Annie On-On, Wu Tsung-Teh, Issa Jean-Pierre J, Hamilton Stanley R, Rashid Asif

Abstract excerpt

BACKGROUND & AIMS: Carcinomas of the extrahepatic bile ducts, ampulla of Vater, and duodenum are uncommon, and their epigenetic and genetic alterations are not well characterized. METHODS: We therefore compared the methylation profile and genetic alterations in 18 extrahepatic biliary, 9 ampullary, and 12 duodenal carcinomas. We evaluated methylation at p16, p14, and human Mut L homologue (hMLH1) by methylation-...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biliary Tract Neoplasms
Share to Calcium Channels, T-Type

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Duodenal Neoplasms

Share to O(6)-Methylguanine-DNA Methyltransferase

Share to Prostaglandin-Endoperoxide Synthases

Share to Receptor, Transforming Growth Factor-beta Type II

Share to Receptors, Retinoic Acid

Share to Receptors, Transforming Growth Factor beta

Source

Identifiers

PMID: 12730870
DOI: 10.1016/s0016-5085(03)00278-6

Genes

MGMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetic and genetic alterations in duodenal carcinomas are distinct from biliary and ampullary carcinomas.PMID 12730870Read ↗

CpG island methylation in carcinoid and pancreatic endocrine tumors.Semantic proximity Read ↗

Aberrant DNA Methylation in CholangiocarcinomaSemantic proximity Read ↗

Integrated genetic and epigenetic analysis of cancer-related genes in non-ampullary duodenal adenomas and intramucosal adenocarcinomas.Semantic proximity Read ↗

Genome wide analysis and clinical correlation of chromosomal and transcriptional mutations in cancers of the biliary tract.Semantic proximity Read ↗

Rare CpG island methylator phenotype in ulcerative colitis-associated neoplasias.Semantic proximity Read ↗

Aberrant DNA Methylation as a Biomarker and a Therapeutic Target of CholangiocarcinomaSemantic proximity Read ↗

Methylation status of genes in non-neoplastic mucosa from patients with ulcerative colitis-associated colorectal cancer.Semantic proximity Read ↗

Epigenome‐Wide Analysis of Methylation Changes in the Sequence of Gallstone Disease, Dysplasia, and Gallbladder CancerSemantic proximity Read ↗

CpG Island Methylator Phenotype–Positive Tumors in the Absence of MLH1 Methylation Constitute a Distinct Subset of Duodenal Adenocarcinomas and Are Associated with Poor PrognosisSemantic proximity Read ↗

Ampullary carcinoma of the duodenum: current clinical issues and genomic overview.Semantic proximity Read ↗

Methylation Profiles of Multiple CpG Island Loci in Extrahepatic Cholangiocarcinoma Versus Those of Intrahepatic CholangiocarcinomasSemantic proximity Read ↗

Histopathologic features and microsatellite instability of cancers of the papilla of vater and their precursor lesions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.