Article
Impact of human leukocyte antigen-B*51-restricted cytotoxic T-lymphocyte pressure on mutation patterns of nonnucleoside reverse transcriptase inhibitor resistance.
AIDS (London, England) - 13 Mar 2010
Gatanaga Hiroyuki, Ode Hirotaka, Hachiya Atsuko, Hayashida Tsunefusa, Sato Hironori, Takiguchi Masafumi, Oka Shinichi
Abstract excerpt
OBJECTIVE: The objective of this study is to determine the impact of human leukocyte antigen (HLA)-B*51-restricted cytotoxic T-lymphocyte (CTL) pressure on the development of nonnucleoside reverse transcriptase inhibitor (NNRTI) resistance. DESIGN: The prevalence of HIV-1 harboring an escape muta...
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