Exploring the Causal Effects of 731 Immune Cell Phenotypes on Asthma: A Bidirectional Two-Sample Mendelian Randomization Study

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold>Asthma is a common chronic respiratory condition characterized by reversible airflow obstruction, bronchial hyperresponsiveness, and inflammation, influenced by genetic predispositions, environmental exposures, and immune responses. Current treatments focus primarily on symptom management, underscoring the need for a deeper understanding of the disease mechanisms...

Topics

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• Asthma
• Dendritic Cells
• Genetic Predisposition to Disease
• Genome-Wide Association Study
• Killer Cells, Natural
• Mendelian Randomization Analysis
• Phenotype
• Polymorphism, Single Nucleotide

Identifiers and source

Literature Corpus work

3c4dd083-7555-5a31-8020-04c88ea026ca

DOI

10.21203/rs.3.rs-4560690/v1