Article
Surviving in the cold: yeast mutants with extended hibernating lifespan are oxidant sensitive.
Aging - 4 Dec 2009
Postma Lucie, Lehrach Hans, Ralser Markus
Abstract excerpt
Metabolic activity generates oxidizing molecules throughout life, but it is still debated if the resulting damage of macromolecules is a causality, or consequence, of the aging process. This problem demands for studying growth- and longevity phenotypes separately. Here, we assayed a complete collection of haploid Saccharomyces cerevisiae knock-out strains for their capacity to endure long periods at low metabolic...
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