Calorie Restriction Suppresses Premature Ageing in Pro-Apoptotic Yeast Mutants Through an Autophagy-Independent Mechanism.

Abstract excerpt

The budding yeast Saccharomyces cerevisiae has long served as a valuable model for investigating the molecular mechanisms underlying aging. Calorie restriction (CR) is a well-established intervention that extends lifespan across species, yet the underlying molecular mechanisms remain incompletely understood. In this study, we examined the effects of CR on the chronological lifespan, oxidative stress response, and...

Topics

Join the communities discussing this publication.

• Apoptosis
• Autophagy
• Caloric Restriction
• Mutation
• Oxidative Stress