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Article

The transcriptome of prematurely aging yeast cells is similar to that of telomerase-deficient cells.

Molecular biology of the cell - 1 Mar 2004

Lesur Isabelle, Campbell Judith L

Abstract excerpt

To help define the pathologies associated with yeast cells as they age, we analyzed the transcriptome of young and old cells isolated by elutriation, which allows isolation of biochemical quantities of old cells much further advanced in their life span than old cells prepared by the biotin-streptavidin method. Both 18-generation-old wild-type yeast and 8-generation-old cells from a prematurely aging mutant...

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Identifiers

PMID: 14718559
DOI: 10.1091/mbc.e03-10-0742
PMCID: PMC363132

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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