Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A variant near the interleukin-6 gene is associated with fat mass in Caucasian men.

International journal of obesity (2005) - 1 Jun 2010

Andersson N, Strandberg L, Nilsson S, Adamovic S, Karlsson M K, Ljunggren O, Mellström D, Lane N E, Zmuda J M, Nielsen C, Orwoll E, Lorentzon M, Ohlsson C, Jansson J-O

Abstract excerpt

CONTEXT: Regulation of fat mass appears to be associated with immune functions. Studies of knockout mice show that endogenous interleukin (IL)-6 can suppress mature-onset obesity. OBJECTIVE: To systematically investigate associations of single nucleotide polymorphisms (SNPs) near the IL-6 (IL6) and IL-6 receptor (IL6R) genes with body fat mass, in support for our hypothesis that variants of these genes can be...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Absorptiometry, Photon
Share to Adiposity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Body Mass Index

Share to Cross-Sectional Studies

Share to Interleukin-6

Share to Obesity

Share to Receptors, Interleukin-6

Share to Sweden

Source

Open in PubMed Open full text

Identifiers

PMID: 20157327
DOI: 10.1038/ijo.2010.27
PMCID: PMC2885503

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A variant near the interleukin-6 gene is associated with fat mass in Caucasian men.PMID 20157327Read ↗

IL6 and IL1B polymorphisms are associated with fat mass in older men: the MrOS Study Sweden.Semantic proximity Read ↗

Variants of the interleukin-1 receptor antagonist gene are associated with fat mass in men.Semantic proximity Read ↗

Interleukin-1 system gene polymorphisms are associated with fat mass in young men.Semantic proximity Read ↗

Polymorphisms in the interleukin-6 receptor gene are associated with bone mineral density and body mass index in Spanish postmenopausal women.Semantic proximity Read ↗

Interleukin-6 genetic variability and adiposity: associations in two prospective cohorts and systematic review in 26,944 individuals.Semantic proximity Read ↗

Functional IL6R 358Ala allele impairs classical IL-6 receptor signaling and influences risk of diverse inflammatory diseases.Semantic proximity Read ↗

Polymorphisms in the interleukin-6 receptor gene are associated with body mass index and with characteristics of the metabolic syndrome.Semantic proximity Read ↗

The interleukin 6 −174G/C Polymorphism is associated with indices of obesity in menSemantic proximity Read ↗

Interleukin-6 gene polymorphism is related to bone mineral density during and after puberty in healthy white males: a cross-sectional and longitudinal study.Semantic proximity Read ↗

Molecular screening and association analyses of the interleukin 6 receptor gene variants with type 2 diabetes, diabetic nephropathy, and insulin sensitivity.Semantic proximity Read ↗

Interactions of interleukin-6 promoter polymorphisms with dietary and lifestyle factors and their association with bone mass in men and women from the Framingham Osteoporosis Study.Semantic proximity Read ↗

Interleukin-6 (IL6) genotype is associated with fat-free mass in men but not women.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.