Article
Polymorphisms in the interleukin-6 receptor gene are associated with bone mineral density and body mass index in Spanish postmenopausal women.
European journal of endocrinology - 1 Nov 2007
Bustamante M, Nogués X, Mellibovsky L, Agueda L, Jurado S, Cáceres E, Blanch J, Carreras R, Díez-Pérez A, Grinberg D, Balcells S
Abstract excerpt
OBJECTIVE: Osteoporosis and obesity are complex diseases with a strong genetic component. Bone mineral density (BMD) and body mass index (BMI) linkage studies identified a locus at 1q21-23, where the interleukin-6 receptor (IL6R) gene is located. The IL6R and the gp130 receptors are the mediators...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
