Article
Glucocorticoid receptor gene polymorphisms and potential association to chronic obstructive pulmonary disease susceptibility and severity.
European journal of medical research - 7 Dec 2009
Schwabe K, Vacca G, Dück R, Gillissen A
Abstract excerpt
OBJECTIVE: As chronic obstructive pulmonary disease (COPD) is known for poor glucocorticoid (GC) response, we hypothesized that polymorphic variants of the glucocorticoid receptor (GR) gene might predispose for COPD and/or disease severity. MATERIAL AND METHODS: Three out of about 50 of the most abundant receptor GR gene polymorphisms were investigated in a case-control study which included 207 patients with...
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