Article
Glucocorticoid receptor gene polymorphisms associated with progression of lung disease in young patients with cystic fibrosis.
Respiratory research - 29 Nov 2007
Corvol Harriet, Nathan Nadia, Charlier Celine, Chadelat Katarina, Le Rouzic Philippe, Tabary Olivier, Fauroux Brigitte, Henrion-Caude Alexandra, Feingold Josue, Boelle Pierre-Yves, Clement Annick
Abstract excerpt
BACKGROUND: The variability in the inflammatory burden of the lung in cystic fibrosis (CF) patients together with the variable effect of glucocorticoid treatment led us to hypothesize that glucocorticoid receptor (GR) gene polymorphisms may affect glucocorticoid sensitivity in CF and, consequentl...
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