Article
The regulation and role of the periplasmic copper, zinc superoxide dismutase of Escherichia coli.
Molecular microbiology - 1 Apr 1999
Gort A S, Ferber D M, Imlay J A
Abstract excerpt
The discovery of superoxide dismutase (CuZnSOD) within the periplasms of several Gram-negative pathogens suggested that this enzyme evolved to protect cells from exogenous sources of superoxide, such as the oxidative burst of phagocytes. However, its presence in some non-pathogenic bacteria implies that there may be a role for this SOD during normal growth conditions. We found that sodC, the gene that encodes the...
Topics
- Alleles
- Bacterial Proteins
- Cell Survival
- Cells, Cultured
- Copper
- Escherichia coli
- Escherichia coli Proteins
- Genotype
- Hydrogen Peroxide
- Oxidative Stress
- Periplasm
- Phenotype
- Plasmids
- Recombinant Fusion Proteins
- Salmonella typhimurium
- Sigma Factor
- Superoxide Dismutase
- Time Factors
