Article
Functional interactions between the carbon and iron utilization regulators, Crp and Fur, in Escherichia coli.
Journal of bacteriology - 1 Feb 2005
Zhang Zhongge, Gosset Guillermo, Barabote Ravi, Gonzalez Claudio S, Cuevas William A, Saier Milton H
Abstract excerpt
In Escherichia coli, the ferric uptake regulator (Fur) controls expression of the iron regulon in response to iron availability while the cyclic AMP receptor protein (Crp) regulates expression of the carbon regulon in response to carbon availability. We here identify genes subject to significant changes in expression level in response to the loss of both Fur and Crp. Many iron transport genes and several carbon...
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