Article
Effect of the global redox sensing/regulation networks on Escherichia coli and metabolic flux distribution based on C-13 labeling experiments.
Metabolic engineering - 1 Nov 2006
Zhu Jiangfeng, Shalel-Levanon Sagit, Bennett George, San Ka-Yiu
Abstract excerpt
Escherichia coli has several elaborate sensing mechanisms for response to the availability of oxygen and the presence of other electron acceptors. Among them, the one component Fnr protein and the two-component Arc system coordinate the adaptive responses to oxygen availability. To systematically investigate the contribution of Arc- and Fnr-dependent regulation in catabolism, glucose-limited chemostat cultures...
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