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Article

Protective action of tetramethylpyrazine phosphate against dilated cardiomyopathy in cTnT(R141W) transgenic mice.

Acta pharmacologica Sinica - 1 Mar 2010

Zhao Hai-ping, Lü Dan, Zhang Wei, Zhang Li, Wang Shu-mei, Ma Chun-mei, Qin Chuan, Zhang Lian-feng

Abstract excerpt

AIM: Dilated cardiomyopathy (DCM) is the most common cause of heart failure, and pharmacological intervention is not currently available. Here we investigate the effect of tetramethylpyrazine phosphate (TMPP) on the progression of DCM in the cTnT(R141W) transgenic mouse model. METHODS: The cTnT(R141W) transgenic mice aged 2 months were divided into model group and TMPP group, whereas age-matched nontransgenic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20154713
DOI: 10.1038/aps.2010.6
PMCID: PMC4002419

Genes

ACTA1

Provenance

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