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Article

The changes of the cardiac structure and function in cTnTR141W transgenic mice.

International journal of cardiology - 1 Aug 2008

Juan Feng, Wei Dong, Xiongzhi Quan, Ran Di, Chunmei Ma, Lan Huang, Chuan Qin, Lianfeng Zhang

Abstract excerpt

OBJECTIVE: To establish the transgenic mouse of cTnT(R141W) gene to make an animal model of dilated cardiomyopathy. METHODS: A transgenic plasmid was constructed by inserting the cTnT(R141W) gene driven by the alpha-MHC promoter. The expression level of the gene was determined with Northern blotting. Pathologic changes were observed by light microscopy and transmission electronic microscopy and analyzed with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18606313
DOI: 10.1016/j.ijcard.2008.03.006

Genes

ACTA1
NPPB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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