Article
Characterization of variations in IL23A and IL23R genes: possible roles in multiple sclerosis and other neuroinflammatory demyelinating diseases.
Aging - 26 Nov 2016
Li Fei-Feng, Zhu Xi-Dong, Yan Peng, Jin Mei-Hua, Yue Hui, Zhang Qiong, Fu Jin, Liu Shu-Lin
Abstract excerpt
Multiple sclerosis is among the most serious inflammatory demyelinating diseases (IDD). Interleukin-23A (IL23A) regulates and coordinates the activities of immune cells by interacting with its receptor IL23R and plays key roles in the pathogenesis of immune inflammatory diseases. IDD, deemed to be a kind of autoimmune diseases, may involve IL23A in the pathogenesis. The aim of this work was to validate the...
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