Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comparative genomics of Streptococcus pyogenes M1 isolates differing in virulence and propensity to cause systemic infection in mice.

International journal of medical microbiology : IJMM - 1 Sept 2015

Fiebig Anne, Loof Torsten G, Babbar Anshu, Itzek Andreas, Koehorst Jasper J, Schaap Peter J, Nitsche-Schmitz D Patric

Abstract excerpt

Streptococcus pyogenes serotype M1 is a frequent cause of severe infections in humans. Some M1 isolates are pathogenic in mice and used in studies on infection pathogenesis. We observed marked differences in murine infections caused by M1 strain SF370, 5448, 5448AP or AP1 which prompted us to sequence the whole genome of isolates 5448 and AP1 for comparative analysis. Strain 5448 is known to acquire inactivating...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Bacteriophages

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Comparative Genomic Hybridization

Share to Exotoxins

Share to Gene Expression Regulation, Bacterial

Share to Mice, Inbred C57BL

Share to Streptococcal Infections

Share to Streptococcus pyogenes

Source

Identifiers

PMID: 26129624
DOI: 10.1016/j.ijmm.2015.06.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comparative genomics of Streptococcus pyogenes M1 isolates differing in virulence and propensity to cause systemic infection in mice.PMID 26129624Read ↗

M1UK Streptococcus pyogenes causing community-acquired pneumonia, pleural empyema and streptococcal toxic shock syndromeSemantic proximity Read ↗

Characterization of a novel covS SNP identified in Australian group A Streptococcus isolates derived from the M1UK lineage.Semantic proximity Read ↗

Complete Genome Sequence of emm Type 14 Streptococcus pyogenes Strain HSC5Semantic proximity Read ↗

Molecular Characteristics of Streptococcus pyogenes Isolated From Chinese Children With Different DiseasesSemantic proximity Read ↗

Dissection of the molecular basis for hypervirulence of an in vivo-selected phenotype of the widely disseminated M1T1 strain of group A Streptococcus bacteria.Semantic proximity Read ↗

Contemporary Pharyngeal and Invasive emm1 and Invasive emm12 Group A Streptococcus Isolates Exhibit Similar In Vivo Selection for CovRS Mutants in Mice.Semantic proximity Read ↗

Complete genome sequence of an M1 strain of <i>Streptococcus pyogenes</i>Semantic proximity Read ↗

Chromosomal islands of Streptococcus pyogenes and related streptococci: molecular switches for survival and virulence.Semantic proximity Read ↗

A variable region within the genome of Streptococcus pneumoniae contributes to strain-strain variation in virulence.Semantic proximity Read ↗

An in vivo atlas of host-pathogen transcriptomes during Streptococcus pneumoniae colonization and disease.Semantic proximity Read ↗

Characterization of Streptococcus pyogenes isolates from French children: emm-1 genotype is associated with invasive infections and spread of the M1UK clone.Semantic proximity Read ↗

Detection of Streptococcus pyogenes M1UK in Australia and characterization of the mutation driving enhanced expression of superantigen SpeA.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.