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Article

Human ELG1 regulates the level of ubiquitinated proliferating cell nuclear antigen (PCNA) through Its interactions with PCNA and USP1.

The Journal of biological chemistry - 2 Apr 2010

Lee Kyoo-Young, Yang Kailin, Cohn Martin A, Sikdar Nilabja, D'Andrea Alan D, Myung Kyungjae

Abstract excerpt

The level of monoubiquitinated proliferating cell nuclear antigen (PCNA) is closely linked with DNA damage bypass to protect cells from a high level of mutagenesis. However, it remains unclear how the level of monoubiquitinated PCNA is regulated. Here, we demonstrate that human ELG1 protein, whic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fanconi Anemia Complementation Group D2 Protein

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Source

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Identifiers

PMID: 20147293
DOI: 10.1074/jbc.M109.092544
PMCID: PMC2856242

Genes

PCNA
USP1
FANCD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20147293-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Human ELG1 regulates the level of ubiquitinated proliferating cell nuclear antigen (PCNA) through Its interactions with PCNA and USP1.PMID 20147293Read ↗

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