Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The functional Toll-like receptor 4 Asp299Gly polymorphism is associated with lower left ventricular mass in hypertensive women.

Clinica chimica acta; international journal of clinical chemistry - 2 May 2010

Sales Maria L, Schreiber Roberto, Ferreira-Sae Maria C S, Fernandes Maruska N, Piveta Cristiane, Cipolli José A A, Calixto Antônio, Matos-Souza José R, Geloneze Bruno, Franchini Kleber G, Nadruz Wilson

Abstract excerpt

BACKGROUND: This study investigated the impact of a putative functional TLR4 polymorphism (Asp299Gly) on left ventricular (LV) structure in hypertensive subjects. METHODS: A sample of 443 patients (266 women and 177 men) was evaluated by clinical history, physical examination, anthropometry, analysis of inflammatory and metabolic parameters, echocardiography and TLR4 Asp299Gly genotyping. In addition, the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Albuminuria
Share to Angiotensin-Converting Enzyme Inhibitors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Calcium Channel Blockers

Share to Creatinine

Share to Echocardiography

Share to Heart Ventricles

Share to Hypertrophy, Left Ventricular

Share to Toll-Like Receptor 4

Source

Identifiers

PMID: 20146922
DOI: 10.1016/j.cca.2010.02.006

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The functional Toll-like receptor 4 Asp299Gly polymorphism is associated with lower left ventricular mass in hypertensive women.PMID 20146922Read ↗

Toll-like receptor 6 Ser249Pro polymorphism is associated with lower left ventricular wall thickness and inflammatory response in hypertensive women.Semantic proximity Read ↗

Impact of the PPARGC1A Gly482Ser polymorphism on left ventricular structural and functional abnormalities in patients with hypertension.Semantic proximity Read ↗

Association of the beta-1 adrenergic receptor carboxyl terminal variants with left ventricular hypertrophy among diabetic and non-diabetic survivors of acute myocardial infarction.Semantic proximity Read ↗

Role of the C-344T aldosterone synthase gene variant in left ventricular mass and left ventricular structure-related phenotypes.Semantic proximity Read ↗

Association of hypo-responsive toll-like receptor 4 variants with risk of myocardial infarction.Semantic proximity Read ↗

Role of the angiotensin II type 2 receptor gene (+1675G/A) polymorphism on left ventricular hypertrophy and geometry in treated hypertensive patients.Semantic proximity Read ↗

The Asp299Gly Toll-like receptor 4 polymorphism in advanced aortic atherosclerosis.Semantic proximity Read ↗

Variants of tumor necrosis factor-induced protein 3 gene are associated with left ventricular hypertrophy in hypertensive patients.Semantic proximity Read ↗

Atrial natriuretic peptide gene promoter polymorphism is associated with left ventricular hypertrophy in hypertension.Semantic proximity Read ↗

Interleukin-6 -634C>G polymorphism in hypertensive patients with and without left ventricular hypertrophy.Semantic proximity Read ↗

Matrix metalloproteinase 9 gene haplotypes affect left ventricular hypertrophy in hypertensive patients.Semantic proximity Read ↗

Variants of toll-like receptor 4 modify the efficacy of statin therapy and the risk of cardiovascular events.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.