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Article

Toll-like receptor 6 Ser249Pro polymorphism is associated with lower left ventricular wall thickness and inflammatory response in hypertensive women.

American journal of hypertension - 1 Jun 2010

Sales Maria L, Schreiber Roberto, Ferreira-Sae Maria C S, Fernandes Maruska N, Piveta Cristiane S C, Cipolli José A A, Cardoso Cátia C, Matos-Souza José R, Geloneze Bruno, Franchini Kleber G, Nadruz Wilson

Abstract excerpt

BACKGROUND: Experimental data demonstrated that inactivation of toll-like receptor (TLR) pathway components attenuated left ventricular (LV) remodeling induced by pressure overload. This study investigated the impact of TLR6 Ser249Pro polymorphism on LV structure in hypertensive subjects. METHODS: A sample of 443 patients (266 women and 177 men) was evaluated by clinical history, physical examination, analysis of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20224557
DOI: 10.1038/ajh.2010.24

Genes

TLR6
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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