Article
BDNF variant Val66Met interacts with estrous cycle in the control of hippocampal function.
Proceedings of the National Academy of Sciences of the United States of America - 2 Mar 2010
Spencer Joanna L, Waters Elizabeth M, Milner Teresa A, Lee Francis S, McEwen Bruce S
Abstract excerpt
Natural fluctuations in circulating estradiol are associated with behavioral changes, including severe disturbances in mood and cognition in some women. Common genetic variation in some of the molecular mediators of estradiol effects on these behaviors, in brain regions such as the hippocampus, may explain individual variation in estradiol effects on behavior. We tested whether the common human variant BDNF...
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