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Article

Genetic variation in brain-derived neurotrophic factor and human fear conditioning.

Genes, brain, and behavior - 1 Feb 2009

Hajcak G, Castille C, Olvet D M, Dunning J P, Roohi J, Hatchwell E

Abstract excerpt

Brain-derived neurotrophic factor (BDNF) has been implicated in hippocampal-dependent learning processes, and carriers of the Met allele of the Val66Met BDNF genotype are characterized by reduced hippocampal structure and function. Recent nonhuman animal work suggests that BDNF is also crucial for amygdala-dependent associative learning. The present study sought to examine fear conditioning as a function of the...

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Identifiers

PMID: 19220486
DOI: 10.1111/j.1601-183X.2008.00447.x
PMCID: PMC4345410

Genes

BDNF

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