Article
Only slight impact of predicted replicative capacity for therapy response prediction.
PloS one - 3 Feb 2010
Weisser Hendrik, Altmann André, Sierra Saleta, Incardona Francesca, Struck Daniel, Sönnerborg Anders, Kaiser Rolf, Zazzi Maurizio, Tschochner Monika, Walter Hauke, Lengauer Thomas
Abstract excerpt
BACKGROUND: Replication capacity (RC) of specific HIV isolates is occasionally blamed for unexpected treatment responses. However, the role of viral RC in response to antiretroviral therapy is not yet fully understood. MATERIALS AND METHODS: We developed a method for predicting RC from genotype u...
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