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Article

Antiretroviral therapy optimisation without genotype resistance testing: a perspective on treatment history based models.

PloS one - 29 Oct 2010

Prosperi Mattia C F, Rosen-Zvi Michal, Altmann André, Zazzi Maurizio, Di Giambenedetto Simona, Kaiser Rolf, Schülter Eugen, Struck Daniel, Sloot Peter, van de Vijver David A, Vandamme Anne-Mieke, Sönnerborg Anders

Abstract excerpt

BACKGROUND: Although genotypic resistance testing (GRT) is recommended to guide combination antiretroviral therapy (cART), funding and/or facilities to perform GRT may not be available in low to middle income countries. Since treatment history (TH) impacts response to subsequent therapy, we inves...

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Identifiers

PMID: 21060792
DOI: 10.1371/journal.pone.0013753
PMCID: PMC2966424

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21060792-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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