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Article

Higher CD4+T Cell Counts Associated with Low ViralpolReplication Capacity among Treatment‐Naive Adults in Early HIV‐1 Infection

25 Jun 2004

Abstract excerpt

BACKGROUND: Infection with primary drug-resistant human immunodeficiency virus type 1 (HIV-1) has been associated with higher CD4(+) T cell counts in drug-naive patients, suggesting that altered viral pol replication capacity (RC) associated with drug resistance diminishes immune injury in vivo, independent of exposure to drugs. METHODS: Virus replication over a single cycle was measured by use of a viral test...

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PMID: 15216458
DOI: 10.1086/422036

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