Microsecond protein folding through a compact transition state.

doi:10.1006/jmbi.1996.0577

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Article

Microsecond protein folding through a compact transition state.

Journal of molecular biology - 25 Oct 1996

Burton R E, Huang G S, Daugherty M A, Fullbright P W, Oas T G

Abstract excerpt

Dynamic NMR methods have been employed to measure the folding and unfolding rate constants of two extremely fast-folding proteins. lambda 6-85, a truncated, monomeric form of the N-terminal domain of lambda repressor, refolds with a lifetime of approximately 250 microseconds. These methods have a...

Topics

DNA-Binding Proteins
Kinetics
Mutation
Protein Folding
Repressor Proteins
Viral Proteins
Viral Regulatory and Accessory Proteins

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