Article
The Association Between Matrix Metalloproteinase-1, -2, -3, -9, and -12 Gene Polymorphisms and Atrial Fibrillation.
International journal of molecular sciences - 27 Jul 2026
Błaszczyk Robert, Sawonik Sebastian, Korona-Głowniak Izabela, Wysocka Anna, Czuba Monika, Świstowska Małgorzata, Król Olgierd, Kocki Janusz, Wysokiński Andrzej, Głowniak Andrzej
Abstract excerpt
Atrial fibrillation (AF) is a prevalent cardiac arrhythmia associated with significant morbidity and mortality. Structural remodeling of the left atrium, particularly myocardial fibrosis, plays a key role in AF pathogenesis. Matrix metalloproteinases (MMPs) are critical regulators of extracellular matrix remodeling and may contribute to atrial fibrosis through genetic variation. This case-control study included...
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