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Expression of CD152 (CTLA-4) in children with autoimmune thyroiditis and +49 A/G polymorphism of exon 1 of the CTLA-4 gene.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society - 1 Nov 2009

Kucharska A M, Gorska E, Wasik M, Pyrzak B, Demkow U

Abstract excerpt

CTLA-4 gene is one of the strongest locus of genetic susceptibility to autoimmune thyroid diseases. The aim of the present study was to investigate surface expression of CTLA-4 on peripheral T cells in homozygotes AA and GG at position +49 of CTLA-4 gene in children with Hashimoto's thyroiditis and in healthy controls. Blood samples were obtained from 100 children: 45 with Hashimoto's thyroiditis and 55 controls....

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Antigens, CD
Child
CTLA-4 Antigen
Exons
Gene Expression Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Restriction Fragment Length

Polymorphism, Single-Stranded Conformational

Thyroiditis, Autoimmune

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PMID: 20134044

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Expression of CD152 (CTLA-4) in children with autoimmune thyroiditis and +49 A/G polymorphism of exon 1 of the CTLA-4 gene.PMID 20134044Read ↗

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