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Article

Association between CTLA-4 + 49A > G and - 318C > T single-nucleotide polymorphisms and susceptibility to thyroid neoplasm.

Endocrine - 1 Oct 2018

Abtahi Shabnam, Izadi Jahromi Fatemeh, Dabbaghmanesh Mohammad Hossein, Malekzadeh Mahyar, Ghaderi Abbas

Abstract excerpt

PURPOSE: Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4 or CD152) is among the immune checkpoint molecules and its abnormal expression in cancer predisposed individuals might make the person more susceptible to tumor initiation and progression. Considering the implication of single-nucleotide polymorphisms (SNPs) in CTLA-4 gene expression and probably protein function, one can assume the involvement of these SNPs in...

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Source

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PMID: 30078171
DOI: 10.1007/s12020-018-1663-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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