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Article

CTLA-4 and its role in autoimmune thyroid disease.

Journal of molecular endocrinology - 1 Aug 2003

Chistiakov D A, Turakulov R I

Abstract excerpt

Autoimmune thyroid disease (AITD) occurs in two common forms: Graves' disease and Hashimoto thyroiditis. On the basis of functional and experimental data, it has been suggested that the gene encoding cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) is a candidate gene for conferring susceptibility to thyroid autoimmunity. In this review, we critically evaluate the evidence for pathogenetic involvement of...

Topics

Antigens, CD
Antigens, Differentiation
CTLA-4 Antigen
Genetic Predisposition to Disease
Genetic Variation
Graves Disease
Humans
Immunoglobulin Fc Fragments
Polymorphism, Genetic
T-Lymphocytes
Thyroiditis, Autoimmune

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12914522
DOI: 10.1677/jme.0.0310021

Genes

CTLA4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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