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Article

5-Lipoxygenase pathway gene polymorphisms: lack of association with asthma in a Spanish population.

Journal of investigational allergology & clinical immunology - 1 Jan 2009

Torres-Galván S M J, Cumplido J A, Buset N, Caballero-Hidalgo A, Blanco C, Hernández E, Carrillo T

Abstract excerpt

BACKGROUND: Cysteinyl-leukotrienes are mediators of inflammatory responses in bronchial asthma. We studied the genes encoding the enzymes involved in their synthesis to identify risk factors for asthma. The promoter polymorphisms LTC4S -444 A/C, ALOX5 -176/-147, and ALOX5AP -169/-146 have been re...

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Source

Identifiers

PMID: 20128419

Genes

ALOX5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20128419-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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