Article
A mouse line expressing <i>Sall1</i>‐driven inducible Cre recombinase in the kidney mesenchyme
1 Feb 2010
Abstract excerpt
Sall1 is expressed in the metanephric mesenchyme in the developing kidney, and mice deficient in Sall1 show kidney agenesis or dysgenesis. Sall1 is also expressed elsewhere, including in the limb buds, anus, heart, and central nervous system. Dominant-negative mutations of Sall1 in mice and humans lead to developmental defects in these organs. Here, we generated a mouse line expressing tamoxifen-inducible Cre...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
