Article
A Sall1-NuRD interaction regulates multipotent nephron progenitors and is required for loop of Henle formation.
Development (Cambridge, England) - 1 Sept 2017
Basta Jeannine M, Robbins Lynn, Denner Darcy R, Kolar Grant R, Rauchman Michael
Abstract excerpt
The formation of the proper number of nephrons requires a tightly regulated balance between renal progenitor cell self-renewal and differentiation. The molecular pathways that regulate the transition from renal progenitor to renal vesicle are not well understood. Here, we show that Sall1interacts with the nucleosome remodeling and deacetylase complex (NuRD) to inhibit premature differentiation of nephron...
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