Article
Kidney development conserved over species: essential roles of Sall1.
Seminars in cell & developmental biology - 1 Aug 2003
Nishinakamura Ryuichi
Abstract excerpt
The kidney develops in three stages: pronephros, mesonephros, and metanephros. Molecular mechanisms underlying these three steps are similar, and we can thus examine genetic cascades occurring during development. The induction system for pronephros in vitro has been established in Xenopus. Using this system, we isolated Sall1 that is essential for the initial step in metanephros formation. The potential...
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