Article
Characterization of a spontaneous avirulent mutant of Legionella pneumophila Serogroup 6: evidence of DotA and flagellin involvement in the loss of virulence.
Journal of microbiology (Seoul, Korea) - 1 Dec 2009
Scaturro Maria, Meschini Stefania, Arancia Giuseppe, Stefano Fontana, Ricci Maria Luisa
Abstract excerpt
The pathogenesis of Legionella pneumophila mainly resides in its ability to inhibit the phagosome-lysosome fusion, which normally prevents the killing of the host cells. In order to characterize the molecular alterations that occurred in a spontaneous avirulent mutant of Legionella pneumophila se...
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