Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of a functional DnaG-type primase in archaea: implications for a dual-primase system.

Journal of molecular biology - 2 Apr 2010

Zuo Zhongfeng, Rodgers Cory J, Mikheikin Andrey L, Trakselis Michael A

Abstract excerpt

We have biochemically characterized the bacterial-like DnaG primase contained within the hyperthermophilic crenarchaeon Sulfolobus solfataricus (Sso) and compared in vitro priming kinetics with those of the eukaryotic-type primase (PriSL) also found in Sso. SsoDnaG exhibited metal- and temperature-dependent profiles consistent with priming at high temperatures. The distribution of primer products was discrete but...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Archaeal Proteins
Share to DNA, Archaeal
Share to DNA Primase

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Electrophoretic Mobility Shift Assay

Share to Eukaryota

Share to Fluorescence Polarization

Share to Glutamic Acid

Share to Sulfolobus solfataricus

Source

Identifiers

PMID: 20122937
DOI: 10.1016/j.jmb.2010.01.057

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of a functional DnaG-type primase in archaea: implications for a dual-primase system.PMID 20122937Read ↗

The heterodimeric primase of the hyperthermophilic archaeon Sulfolobus solfataricus possesses DNA and RNA primase, polymerase and 3'-terminal nucleotidyl transferase activities.Semantic proximity Read ↗

A common sequence motif, -E-G-Y-A-T-A-, identified within the primase domains of plasmid-encoded I- and P-type DNA primases and the alpha protein of the Escherichia coli satellite phage P4.Semantic proximity Read ↗

Structural Insight into the Specific DNA Template Binding to DnaG primase in Bacteria.Semantic proximity Read ↗

Insights into eukaryotic DNA priming from the structure and functional interactions of the 4Fe-4S cluster domain of human DNA primase.Semantic proximity Read ↗

Increased Processivity, Misincorporation, and Nucleotide Incorporation Efficiency in Sulfolobus solfataricus Dpo4 Thumb Domain Mutants.Semantic proximity Read ↗

Crystal structure of the Pyrococcus horikoshii DNA primase-UTP complex: implications for the mechanism of primer synthesis.Semantic proximity Read ↗

DnaG interacts with a linker region that joins the N- and C-domains of DnaB and induces the formation of 3-fold symmetric rings.Semantic proximity Read ↗

Translesion activity of PrimPol on DNA with cisplatin and DNA–protein cross-linksSemantic proximity Read ↗

Engineering human PrimPol into an efficient RNA-dependent-DNA primase/polymerase.Semantic proximity Read ↗

A read-ahead function in archaeal DNA polymerases detects promutagenic template-strand uracil.Semantic proximity Read ↗

Complexed crystal structure of replication restart primosome protein PriB reveals a novel single-stranded DNA-binding mode.Semantic proximity Read ↗

Mechanism and stoichiometry of interaction of DnaG primase with DnaB helicase of Escherichia coli in RNA primer synthesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.