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Article

Complexed crystal structure of replication restart primosome protein PriB reveals a novel single-stranded DNA-binding mode.

Nucleic acids research - 1 Jan 2006

Huang Cheng-Yang, Hsu Che-Hsiung, Sun Yuh-Ju, Wu Huey-Nan, Hsiao Chwan-Deng

Abstract excerpt

PriB is a primosomal protein required for replication restart in Escherichia coli. PriB stimulates PriA helicase activity via interaction with single-stranded DNA (ssDNA), but the molecular details of this interaction remain unclear. Here, we report the crystal structure of PriB complexed with a 15 bases oligonucleotide (dT15) at 2.7 A resolution. PriB shares structural similarity with the E.coli ssDNA-binding...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16899446
DOI: 10.1093/nar/gkl536
PMCID: PMC1557812

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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