Article
Proteomic analysis reveals CCT is a target of Fragile X mental retardation protein regulation in Drosophila.
Developmental biology - 15 Apr 2010
Monzo Kate, Dowd Susan R, Minden Jonathan S, Sisson John C
Abstract excerpt
Fragile X mental retardation protein (FMRP) is an RNA-binding protein that is required for the translational regulation of specific target mRNAs. Loss of FMRP causes Fragile X syndrome (FXS), the most common form of inherited mental retardation in humans. Understanding the basis for FXS has been limited because few in vivo targets of FMRP have been identified and mechanisms for how FMRP regulates physiological...
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