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Article

Fragile X protein functions with lgl and the par complex in flies and mice.

Developmental cell - 1 Jan 2005

Zarnescu Daniela C, Jin Peng, Betschinger Joerg, Nakamoto Mika, Wang Yan, Dockendorff Thomas C, Feng Yue, Jongens Thomas A, Sisson John C, Knoblich Juergen A, Warren Stephen T, Moses Kevin

Abstract excerpt

Fragile X syndrome, the most common form of inherited mental retardation, is caused by loss of function for the Fragile X Mental Retardation 1 gene (FMR1). FMR1 protein (FMRP) has specific mRNA targets and is thought to be involved in their transport to subsynaptic sites as well as translation regulation. We report a saturating genetic screen of the Drosophila autosomal genome to identify functional partners of...

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Source

Identifiers

PMID: 15621528
DOI: 10.1016/j.devcel.2004.10.020

Genes

FMR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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