Article
Defensin-immunology in inflammatory bowel disease.
Gastroenterologie clinique et biologique - 1 Jun 2009
Wehkamp J, Stange E F, Fellermann K
Abstract excerpt
Defensins are endogenous antibiotics with microbicidal activity against Gram-negative and Gram-positive bacteria, fungi, enveloped viruses and protozoa. A disturbed antimicrobial defense, as provided by Paneth- and other epithelial cell defensins, seems to be a critical factor in the pathogenesis...
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