Article

Recent advances in understanding and managing Crohn’s disease

2016-12-21

Abstract excerpt

There is consensus that inflammatory bowel diseases (IBDs) are the result of “dysregulated” immune reactivity towards commensal microorganisms in the intestine. This gut microbiome is clearly altered in IBD, but its primary or secondary role is still debated. The focus has shifted from adaptive to innate immunity, with its multitude of receptor molecules (Toll-like and NOD receptors) and antibacterial effector mol...

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Literature Corpus work: 2ff72135-3fb3-50b6-98ae-799e17d350bd
DOI: 10.12688/f1000research.9890.1

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