Article
Innate antimicrobial immunity in inflammatory bowel diseases.
Expert review of clinical immunology - 1 Sept 2010
Beisner Julia, Stange Eduard F, Wehkamp Jan
Abstract excerpt
Inflammatory bowel diseases are characterized by chronic intestinal inflammation at different sites. Data from animal models as well as human patients including gene-association studies suggest that different components of the innate barrier function are primarily defective. These recent advances support the evolving hypothesis that intestinal bacteria induce inflammation predominantly as a result of a weakened...
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