Article
RSC Nucleosome-remodeling complex plays prominent roles in transcriptional regulation throughout budding yeast gametogenesis.
Bioscience, biotechnology, and biochemistry - 1 Apr 2004
Koyama Hirofumi, Nagao Taka-aki, Inai Tomomi, Miyahara Kohji, Hayasida Yasufumi, Shirahige Katsuhiko, Tsuchiya Eiko
Abstract excerpt
RSC is a nucleosome-remodeling complex of Saccharomyces cerevisiae essential for growth that can alter histone-DNA interaction by using the energy of ATP hydrolysis. Nps1p/Sth1p is an ATPase subunit of RSC. A mutation in the conserved ATPase domain of Nps1p causes a sporulation defect with decreased expression of early meiotic genes, especially IME2. This defect is partially suppressed by the overexpression of...
Topics
- Cell Cycle Proteins
- Cell Division
- Cell Nucleus
- Chromatin Assembly and Disassembly
- Diploidy
- Flow Cytometry
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Intracellular Signaling Peptides and Proteins
- Meiosis
- Mutation
- Nuclear Proteins