Article
Nps1/Sth1p, a component of an essential chromatin-remodeling complex of Saccharomyces cerevisiae, is required for the maximal expression of early meiotic genes.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Feb 1999
Yukawa M, Katoh S, Miyakawa T, Tsuchiya E
Abstract excerpt
BACKGROUND: The NPS1/STH1 gene of Saccharomyces cerevisiae is essential for mitotic growth, especially for the progression through the G2/M phase. It encodes a major component of the chromatin-remodelling complex, RSC, of unknown function. We attempted to address the function of NPS1 in meiosis. RESULTS: The homozygote of the temperature sensitive nps1 mutant, nps1-105, showed reduced and delayed levels of...
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